4099 – HepAK 7plus Dot

4099 – HepAK 7plus Dot

4291 – ANA 18 LINE

Product Specifications

TITLE

4099 – HEPAK 7Plus DOT

Product code


4099

Indication


Autoimmune liver disease

Description

Dot Immunoassay for the qualitative determination of IgG antibodies against M2, gp210, sp100, LKM1, LC1, SLA and F-actin in human serum



Format

Test strips coated with M2, gp210, sp100, LKM1, LC1, SLA and F-actin



Total incubation time


80 min.



Sample volume


10 µL serum



No. of determinations


24 x 7


Intended Purpose

The HepAK 7plus Dot is a qualitative dot immunoassay for the determination of IgG antibodies against M2, gp210, sp100, LKM1, LC1, SLA and F-actin in human serum. The HepAK 7plus Dot is intended as an aid in the diagnosis of autoimmune liver diseases in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use.

Diagnostic Relevance

Primary autoimmune liver disease (PAL), autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC), just like other forms of chronic liver diseases, show autoimmune pathogenesis, the appearance of autoantibodies. This pathogenesis thus points out the need for specific autoantibody determination after the exclusion of infectious etiology e.g. viruses. PSC show intestine related symptoms with ANCA patterns serological diagnosis (e.g. via indirect immunofluorescence) on neutrophils. The occurrence of antibodies to mitochondrial antigens (M2) is typical of PBC. AIH show different autoantibodies, especially autoantibodies to; antinuclear antibodies (ANA), smooth muscles (ASMA), liver and kidney microsomal antigens (LKM),  the soluble liver antigen (SLA).

Contact Firstkbz Nigeria Limited

Kindly fill out the form below to get in touch with Firstkbz Nigeria Limited. Our team will respond promptly to assist you with your inquiries.