4291 – ANA 18 LINE

4291 – ANA 18 LINE

4291 – ANA 18 LINE

Product Specifications

TITLE

4291 – ANA 18 LINE


Product code


4291

Indication


Systemic inflammatory rheumatic diseases

Description

Line immunoassay for the qualitative determination of IgG antibodies against nuclear and cytoplasmic antigens in human serum

Format

Test strips coated with dsDNA, nucleosome, Sm, Sm/RNP, ribosomes, histone, U1-snRNP, SS-A 60, SS-A 52, SS-B, Scl-70, PM/Scl, CENP-A/B, PCNA, Jo-1, M2, DFS-70 and f-Actin

Total incubation time


80 min.

Sample volume


10 µL serum

No. of determinations


20 x 18

Intended Purpose

The ANA 18 LINE is a qualitative line immunoassay for the determination of IgG antibodies against nuclear and cytoplasmic antigens (dsDNA, nucleosome, Sm, Sm/RNP, ribosomes, histone, U1-snRNP, SS-A 60, SS-A 52, SS-B, Scl-70, PM/Scl, CENP-A/B, PCNA, Jo-1, M2, DFS-70 and f-Actin) in human serum. The ANA 18 LINE is intended as an aid in the diagnosis of systemic inflammatory rheumatic diseases in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use.

Diagnostic Relevance

The detection of antibodies in patient samples is well established and plays an essential role in the diagnosis of systemic autoimmune diseases. The appearance of antibodies directed against components of the cell nucleus are characteristic features of systemic autoimmune diseases, especially systemic lupus erythematosus (SLE), Sjögren’s syndrome, progressive systemic sclerosis (PSS), mixed connective tissue disease (MCTD), rheumatoid arthritis (RA) and dermatomyositis.

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